Isosorbide Mononitrate is used for:

Preventing angina (chest pain) caused by heart disease.

Isosorbide Mononitrate is a nitrate vasodilator. It works by widening the blood vessels in the body. This reduces the workload of the heart and helps to relieve chest pain.

Do NOT use Isosorbide Mononitrate if:

• you are allergic to any ingredient in Isosorbide Mononitrate or to other nitrate medicines
• you are also taking a phosphodiesterase type 5 inhibitor (eg, sildenafil, tadalafil, vardenafil)
• you drink alcohol

Contact your doctor or health care provider right away if any of these apply to you.

Before using Isosorbide Mononitrate :

Some medical conditions may interact with Isosorbide Mononitrate. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have heart problems (eg, heart failure, heart attack, hypertrophic cardiomyopathy), low blood pressure, blood problems (eg, anemia), dehydration, bleeding the brain, an overactive thyroid, or have had a recent head injury

Some MEDICINES MAY INTERACT with Isosorbide Mononitrate. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Calcium channel blockers (eg, diltiazem, verapamil) or phosphodiesterase type 5 inhibitors (eg, sildenafil, tadalafil, vardenafil) because the risk of severe low blood pressure may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Isosorbide Mononitrate may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Isosorbide Mononitrate :

Use Isosorbide Mononitrate as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Isosorbide Mononitrate by mouth with or without food.
• This medication should be taken twice daily, with the doses 7 hours apart. The first dose should preferably be taken in the morning upon waking up, unless directed otherwise by your doctor.
• Do not suddenly stop taking Isosorbide Mononitrate. You may have an increased risk of side effects (eg, angina attacks). If you need to stop Isosorbide Mononitrate or add a new medicine, your doctor will gradually lower your dose.
• If you miss a dose of Isosorbide Mononitrate , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Isosorbide Mononitrate.

Important safety information:

• Isosorbide Mononitrate may cause dizziness or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Isosorbide Mononitrate with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Isosorbide Mononitrate may cause dizziness or lightheadedness; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
• Do not drink alcohol while you are taking Isosorbide Mononitrate.
• When you begin taking Isosorbide Mononitrate , headaches are likely to occur. Ask your doctor for instructions on ways to reduce this side effect.
• Isosorbide Mononitrate should not be used to stop an attack of angina; it is intended only for prevention of an attack.
• Isosorbide Mononitrate may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Isosorbide Mononitrate.
• Isosorbide Mononitrate should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Isosorbide Mononitrate while you are pregnant. It is not known if Isosorbide Mononitrate is found in breast milk. If you are or will be breast-feeding while you use Isosorbide Mononitrate , check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Isosorbide Mononitrate :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; headache; nausea.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; fainting; numbness of an arm or leg; severe stomach pain; sharp or crushing chest pain; sudden leg pain; sudden, severe headache; sudden shortness of breath; vomiting.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.

Other Useful Information:

Calcium: A mineral found mainly in the hard part of bones, where it is stored. Calcium is added to bones by cells called osteoblasts and is removed from bones by cells called osteoclasts. Calcium is essential for healthy bones. It is also important for muscle contraction, heart action, nervous system maintenance, and normal blood clotting. Food sources of calcium include dairy foods, some leafy green vegetables such as broccoli and collards, canned salmon, clams, oysters, calcium-fortified foods, and tofu. According to the National Academy of Sciences, adequate intake of calcium is 1,200 milligrams a day (four glasses of milk) for men and women 51 and older, 1,000 milligrams a day for adults 19 through 50, and 1,300 milligrams a day for children 9 through 18. The upper limit for calcium intake is 2.5 grams daily.

Cavities: Holes in the two outer layers of a tooth called the enamel and the dentin. The enamel is the outermost white hard surface and the dentin is the yellow layer just beneath enamel. Both layers serve to protect the inner living tooth tissue called the pulp, where blood vessels and nerves reside. Small cavities may not cause pain, and may be unnoticed by the patient. Larger cavities can collect food, and the inner pulp of the affected tooth can become irritated by bacterial toxins, foods that are cold, hot, sour, or sweet - causing toothache.

Naturopathy: A system of therapy based on preventative care, and on the use of heat, water, light, air, and massage as primary therapies for disease. Some naturopaths use no medications, either pharmaceutical or herbal. Some recommend herbal remedies only. A few who are licensed to prescribe may recommend pharmaceuticals in those cases where they feel their use is warranted.

Naturopathy is an American healthcare profession. It was founded in the US as a formal healthcare system at the turn of the 20th century by medical practitioners from various natural therapeutic disciplines. By the early 1900s, more than 20 naturopathic medical schools existed, and naturopathic physicians were licensed in most States. Today there are more than 1,000 licensed naturopathic doctors in the US.

As practiced today, naturopathic medicine integrates traditional natural therapeutics -- including botanical medicine, clinical nutrition, homeopathy, acupuncture, traditional oriental medicine, hydrotherapy, and naturopathic manipulative therapy -- with modern scientific medical diagnostic science and standards of care. The medical research base of naturopathic practice consists of empirical documentation of treatments using case history observations, medical records, and summaries of practitioners' clinical experiences.

At present, the two accredited naturopathic medical schools in the US have active research departments. Naturopathic researchers have investigated the pharmacology and physiological effects of nutritional and natural therapeutic agents, and naturopathic physicians have been active in the investigation of new homeopathic remedies and in the natural treatment of women's health problems. The most recently completed naturopathic study in women's health tested the clinical and endocrine effects of a botanical formula as an alternative to estrogen replacement therapy.

Blood: The familiar red fluid in the body that contains white and red blood cells, platelets, proteins, and other elements. The blood is transported throughout the body by the circulatory system. Blood functions in two directions: arterial and venous. Arterial blood is the means by which oxygen and nutrients are transported to tissues while venous blood is the means by which carbon dioxide and metabolic by-products are transported to the lungs and kidneys, respectively, for removal from the body.

Blood pressure: The blood pressure is the pressure of the blood within the arteries. It is produced primarily by the contraction of the heart muscle. It's measurement is recorded by two numbers. The first (systolic pressure) is measured after the heart contracts and is highest. The second (diastolic pressure) is measured before the heart contracts and lowest. A blood pressure cuff is used to measure the pressure. Elevation of blood pressure is called "hypertension".

Brain: That part of the central nervous system that is located within the cranium (skull). The brain functions as the primary receiver, organizer and distributor of information for the body. It has two (right and left) halves called "hemispheres."

Disease: Illness or sickness often characterized by typical patient problems (symptoms) and physical findings (signs). Disruption sequence: The events that occur when a fetus that is developing normally is subjected to a destructive agent such as the rubella (German measles) virus.

Doctor: In a medical context, any medical professional with an MD, a PhD, or any other doctoral degree. The term doctor is quite nonspecific. A doctor may, for example, be a physician, psychologist, biomedical scientist, dentist, or veterinarian. In a nonmedical context, a professor of history might be addressed as doctor, an eminent theologian might be named a doctor of a church, and a person awarded an honorary doctorate by a college or university might also be called a doctor.

The word "doctor" comes from the Latin "docere" meaning to teach. A doctor was a teacher, especially a learned or authoritative one.